Daniel J. Sargent, PhD Memorial Fellowship in Innovative Clinical Trial Design and Methods

The Alliance for Clinical Trials in Oncology Foundation offers the Daniel J. Sargent, PhD Memorial Fellowship in Innovative Clinical Trial Design and Methods award for a one-year, non-renewable term each year.

The fellowship award honors the contributions of Dr. Sargent to the field of clinical cancer research. It is open to faculty or master's level statisticians (working with a senior faculty member) within the Alliance Statistics and Data Management Center (SDMC). Proposals must be closely tied to the research agenda of the Alliance and Alliance SDMC. The work proposed should address study design and/or data analysis approaches that are directly relevant to current challenges in the areas of cancer clinical trials. The proposal should address achieving innovation in one or more of the following areas: cancer clinical trial design, prognostic and predictive biomarkers, endpoints, trial conduct, and monitoring, analytical methods, and execution. The work should directly lead to a peer-reviewed publication or preliminary data for a grant proposal. Successful applicants are expected to provide a written progress review at the end of the funding period, with a plan for the publication and/or grant submission.

To learn more about the Sargent Memorial Fellowship, Sumithra Mandrekar, PhD, at mandrekar.sumithra@mayo.edu.

Fellowship Recipients

Nicholas B. Larson, PhD, MS
Associate Professor of Biostatistics, Senior Associate Consultant II-Research, Mayo Clinic
Project: “Leveraging polygenic risk scores as prognostic markers in cancer outcomes”

Paul J. Novotny, MS
- Assistant Professor, Biostatistics, Mayo Clinic 
Project: "Choice of Study Endpoints and Analysis Methods in Symptom Intervention Clinical Trials with Continuous Patient-Report Outcomes: A Monte Carlo Power Analysis and Application to Alliance CIPN and Hot Flash Clinical Trials"

David Zahrieh, PhD,
Assistant Professor, Health Sciences Research - Mayo Clinic 
Project: "Composite Response Endpoint to Evaluate Effectiveness of New Interventions for the Prevention of Oxaliplatin-induced Peripheral Neuropathy"

Vivien (Jun) Yin, PhD, Assistant Professor of Biostatistics, Associate Consultant, and Faculty Statistician - Mayo Clinic
"Individualized Patient Dosing in Phase I Clinical Trials Incorporating Patient-Reported Outcomes"