ASCO COVID-19 Vaccine & Patients with Cancer Statement

January 15, 2021

ASCO 12/22/2020 Statement “COVID-19 Vaccine & Patients with Cancer"
At this time, patients with cancer may be offered vaccination against COVID-19 as long as components of that vaccine are not contraindicated. The current US CDC recommendations around vaccination do not mention cancer but do discuss immunocompromised individuals. They state: “Immunocompromised individuals may st

New Trial Alert: Alliance A011801 HER2-Positive Breast Cancer (COMPASS)

January 11, 2021

Alliance A011801: The CompassHER2 trials (Comprehensive use of pathologic response assessment to optimize therapy in HER2-positive breast cancer) CompassHER2 residual disease (RD), a double-blinded, phase III randomized trial of T-DM1 compared with T-DM1 and tucatinib

Overview: Alliance investigator Ciara C. O'Sullivan, MB, BCh, BAO, of Mayo Clinic, leads this phase III trial that studi

New Trial Alert: Alliance A031901 Metastatic Urothelial Carcinoma

January 11, 2021

Alliance A031901: Duration of immune checkpoint therapy in locally advanced or metastatic urothelial carcinoma: A randomized phase 3 non-inferiority trial

Overview: Alliance investigators Xiao X. Wei, MD, MAS and Toni K. Choueiri, MD, of Dana-Farber Cancer Institute, lead this phase III trial that compares survival in patients with urothelial cancer who stop immune checkpoint inhibitor treatment aft

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