How to Submit a Concept (for the general public)

It is recommended that any treatment concept be discussed with the respective Alliance Committee Chair prior to submission. For committee chair information, send the request to

To submit a treatment concept, use one of two NCI Cancer Therapy Evaluation Program forms: the NCI Letter of Intent (LOI) Submission Form or the NCI Phase II/III Concept Submission Form. These forms can be found on the NCI website. In addition, an Alliance Conflict of Interest Form should accompany the concept submission. Once all forms have been completed, they should be submitted by e-mail to

If you are an Alliance member, log-in to the Alliance member website and visit the protocols section for member-specific details on how to submit a concept.