international collaborations

Alliance International Collaborations (IC) oversee the operational activities of international sites (full member and non-member collaborators) that participate in Alliance trials.  The Alliance IC supports high quality, collaborative research with international groups by helping facilitate and guide international sites through the logistical discussions required for study activation. To learn more about international collaborations at the Alliance, e-mail

Alliance Trials with International Collaborations

A021502Randomized trial of standard chemotherapy alone or combined with atezolizumab as adjuvant therapy for patients with stage III colon cancer and deficient DNA mismatch repair

A031102 - Randomized phase III trial comparing conventional-dose chemotherapy using paclitaxel, ifosfamide, and cisplatin (TIP) with high-dose chemotherapy using mobilizing paclitaxel plus ifosfamide followed by high-dose carboplatin and etoposide (TI-CE) as first salvage treatment in relapsed or refractory germ cell tumors

A211801BRCA-P: A randomized, double-blind, placebo-controlled, multi-center, international phase 3 study to determine the preventive effect of denosumab on breast cancer in women carrying a BRCA1 germline mutation

A221405 A study evaluating the pregnancy outcomes and safety of interrupting endocrine therapy for young women with endocrine responsive breast cancer who desire pregnancy

N1048 - Phase II/II trial of neoadjuvant FOLFOX, with selective use of combined modality chemoradiation versus preoperative combined modality chemoradiation for locally advanced rectal cancer patients undergoing low anterior resection with total mesorectal excision

N0577 - Phase III intergroup study of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy with adjuvant PCV chemotherapy in patients with 1p/19q co-deleted anaplastic glioma or low grade glioma

Helpful Resources
For investigator registration, visit the NCI Investigator Resources website.
To obtain Federal Wide Assurance, visit the OHRP website.