E-Newsletter - September 2021
Spotlight on Alliance Committee Chairs
Alliance expresses gratitude to committee chairs ending terms
This year marks a 10-year milestone for the Alliance for Clinical Trials in Oncology. It also marks a transition for many outstanding Alliance committee chairs because of a 10-year term limit for these positions. What follows is a list of dedicated researchers who have provided distinguished service to the Alliance and will step down from their chair roles effective November 2021, making way for new leaders to carry on.
Richard M. Stone, MD – Chair, Alliance Leukemia Committee. As an international leader in leukemia research, Dr. Stone has guided the Alliance team to develop exciting trials addressing the most important questions in leukemia diagnosis, treatment, and translational science. He has also been a champion of collaboration and coordination between all of the NCI-funded cooperative groups involved in studying leukemia. Dr. Stone is Professor of Medicine at Harvard Medical School and serves as Chief of Staff, and Director of Translational Research for the Adult Acute Leukemia Program at the Dana-Farber Cancer Institute.
Paul G. Richardson, MD – Chair, Alliance Myeloma Committee. Under Dr. Richardson’s mentorship, the committee has conducted important research in the areas of treatment, novel approaches to transplant, and translational science. He has also served as a champion for effective collaboration with international research teams, as well as with other NCI-funded myeloma research teams, to further contribute to improving the outcomes of patients diagnosed with multiple myeloma. Dr. Richardson is the R.J. Corman Professor of Medicine at Harvard Medical School, and the Clinical Program Leader and Director of Clinical Research at the Jerome Lipper Multiple Myeloma Center at the Dana-Farber Cancer Institute.
Eric D. Hsi, MD – Chair, Alliance Pathology Committee. Dr. Hsi has been responsible for leading and organizing efforts to integrate pathology and impactful translational research into Alliance trials across disease site committees, working with other Pathology Committee members and disease site correlative science investigators. His extended and distinguished tenure exemplified his expertise in state-of-the-art pathology practices and translational research. Dr. Hsi is Chair and Professor of Pathology in the Department of Pathology at Wake Forest School of Medicine, and Pathology/Laboratory Medicine Enterprise Service Leader and Academic Chair at Wake Forest Baptist Health, Atrium Health.
Mark J. Ratain, MD – Chair, Alliance Pharmacogenomics and Population Pharmacology Committee - Alliance Translational Research Program. Under Dr. Ratain’s leadership, the committee has led research in pharmacogenomics to understand genetic contributions to variation in drug response and toxicities. An expert in the use of investigational agents to treat advanced solid tumors with a specialty in the clinical pharmacology of marketed drugs, he has championed the importance of clinical pharmacology and inclusion of genetic information in drug dose optimization within the Alliance (10 years) and its legacy group, Cancer and Leukemia Group B (17 years). Dr. Ratain is the Leon O. Jacobson Professor of Medicine at the University of Chicago, and Director of the Center for Personalized Therapeutics and Associate Director for the Clinical Sciences for Comprehensive Cancer Center, and Chief of Hospital Pharmacology at the University of Chicago Medicine.
Charles Loprinzi, MD – Chair, Alliance Symptom Intervention Committee - Alliance Cancer Control Program. During Dr. Loprinzi’s tenure, the committee has led research devoted to the treatment, prevention, or better understanding of unexpected symptoms that are related to cancer, cancer treatment, or both. This work, within the Alliance (10 years) and in its legacy group North Central Cancer Treatment Group, has addressed the management of mouth sores or inflammation of the esophagus or bowels; cancer-related loss of appetite, weight or both chemotherapy-induced hot flashes, skin toxicity, sexuality symptoms, numbness, tingling, pain or a combination; arm swelling; cognitive dysfunction; bone thinning; insomnia; and fatigue. Dr. Loprinzi is a Regis Professor of Breast Cancer Research, Professor of Oncology, and Consultant in the Division of Medical Oncology, Department of Oncology at the Mayo Clinic. His tenure as chair ended in July 2021.
For other articles in this issue of the Alliance E-News newsletter, see below.
- Message From the Group Chair - Monica M. Bertagnolli, MD
- Registration Now Open - 2021 Alliance Fall Virtual Group Meeting
- Alliance Expresses Gratitude to Committee Chairs Ending Terms
- Alliance Welcomes New Committee Leaders
- NCI NCORP Honors Two Alliance Members
-
Spotlight on Alliance Trials
Ten Currently Active Alliance Cancer Control Program/NCORP Research Base Trials
Alliance A171901 - Lung Cancer
Alliance A191901 - Endocrine Therapy Adherence
Alliance A211102 - Testing for Atypia
Alliance A211601 - Mammographic Breast Density
Alliance A221702 - Axillary Reverse Mapping
Alliance A221805 - Peripheral Neuropathy
Alliance A222001 - Reducing Hot Flashes in Men
Alliance A231601CD - Improving Surgical Care/Outcomes (OPIT-Surg)
Alliance A231701CD - Shared Breast Cancer Surgery Decision Making
Alliance A231901CD - Patient-Centered Communication in Breast Cancer
Four Recently Activated Alliance NCTN Trials
Alliance A021901 - Bronchial Neuroendocrine Tumors
Alliance A051902 - Peripheral T-cell Lymphoma
Alliance A031902 - Metastatic Castration-Resistance Prostate Cancer (CASPAR)
Alliance A011801 - HER2-Positive Breast Cancer (CompassHER2)
Closed to Accrual: Alliance A221505 (RT CHARM) -
Alliance Funding Opportunities
Daniel J. Sargent, PhD Memorial Fellowship in Innovative Clinical Trial Design and Methods Award -
Alliance in the News
Patient Perspective in Clinical Trials – Alliance Patient Advocate Julie Krause Interview
Randomized Phase II Study of PET Response–Adapted Combined Modality Therapy for Esophageal Cancer: Mature Results of the CALGB 80803 (Alliance) Trial
Patient Perspective on Clinical Trials - Alliance Patient Advocate Julie Krause
Impact of the COVID-19 Pandemic on Clinical Trials
Combining Tumor Deposits with the Number of Lymph Node Metastases to Improve the Prognostic Accuracy in Stage III Colon Cancer: A Post Hoc Analysis of the CALGB/SWOG 80702 Phase III Study (Alliance)
New ECU, Vidant Partnership Provides Access to Clinical Trials for Rare Cancers
Celecoxib Provides No Survival Benefit for Patients with Stage III Colon Cancer
Disparities in Older Adult Accrual to Cancer Trials: Analysis from the Alliance for Clinical Trials in Oncology (A151736)