E-Newsletter - August 2024
Alliance in the News
ALLIANCE RESEARCH IN THE NEWS & publications
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Palbociclib in adults aged 70 years and older with advanced breast cancer: A phase 2 multicenter trial (Alliance A171601)
Results from a study of palbociclib, which is often used to treat advanced breast cancer in older adults. More research is needed to evaluate its impact on older adults. - Journal of Geriatric Oncology -
Plant-based diet and survival among patients with metastatic colorectal cancer: Findings from CALGB/SWOG 80405 (Alliance)
A study to determine if a plant-based diet may help patients with metastatic colorectal cancer live longer. - 2024 American Association of Cancer Research Annual Meeting
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Fertility preservation and assisted reproduction in patients with breast cancer interrupting adjuvant endocrine therapy to attempt pregnancy
A look at time to pregnancy, efficacy and safety of fertility preservation, and assisted reproductive technologies in women with early hormone receptor–positive breast cancer who desire to get pregnant in the future. - Journal of Clinical Oncology
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Identifying long-term survivors and those at higher or lower risk of relapse among patients with cytogenetically normal acute myeloid leukemia using a high-dimensional mixture cure model
A trial to identify a novel, prognostically relevant molecular signature in patients with cytogenetically normal acute myeloid leukemia. - Journal of Hematology & Oncology
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Myeloablative vs nonmyeloablative consolidation for primary central nervous system lymphoma: Results of Alliance 51101
Results of the "first" randomized trial to be initiated that may eliminate whole-brain radiotherapy as a consolidative approach in newly diagnosed primary central nervous system lymphoma (PCNSL). - Blood Advances
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HER2 gene expression levels are predictive and prognostic in patients with metastatic colorectal cancer enrolled in CALGB/SWOG 80405
A trial looking at the potential prognostic and predictive value of HER2 amplification and gene expression using next-generation sequencing and NanoString data in patients with metastatic colorectal cancer. - Journal of Clinical Oncology -
Aspirin vs placebo as adjuvant therapy for breast cancer: The Alliance A011502 randomized trial
Results of a trial looking to determine whether aspirin decreases the risk of invasive cancer events among survivors of breast cancer. - JAMA
Read more news briefs from this issue:
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Spotlight in Alliance Trials
World Lung Cancer Day
>> Alliance A021901
>> Alliance A081801
>> Alliance A082002
>> Alliance A082101
>> Alliance A151216
>> Alliance A211901 - Alliance Publications Committee: Transition and Progress
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General News and Announcements
>> Alliance Research in the News & Publications
>> Call for Nominations: Richard L. Schilsky CALGB Achievement Award
>> Call ofr Nominations: Charles G. Moertel Lectureship Award
>> Call for Applications: Daniel J. Sargent, PhD Memorial Fellowship in Innovative Clinical Trial Design and Methods